• Targeting of a New Node in Lipid Metabolism as a Potential Treatment Strategy for ACC.
  LaPensee, Christopher R, Hammer, Gary D. Endocrinology. 2023 Jan 09;164(3):. doi:bqad003. Epub .PMID: 36636840
• American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary.
  Yip, Linwah, Duh, Quan-Yang, Wachtel, Heather, Jimenez, Camilo, Sturgeon, Cord, Lee, Cortney, Velázquez-Fernández, David, Berber, Eren, Hammer, Gary D, Bancos, Irina, Lee, James A, Marko, Jamie, Morris-Wiseman, Lilah F, Hughes, Marybeth S, Livhits, Masha J, Han, Mi-Ah, Smith, Philip W, Wilhelm, Scott, Asa, Sylvia L, Fahey, Thomas J, McKenzie, Travis J, Strong, Vivian E, Perrier, Nancy D. JAMA Surg. 2022 Oct 01;157(10):870-877. doi:10.1001/jamasurg.2022.3544. Epub .PMID: 35976622
• Update on Biology and Genomics of Adrenocortical Carcinomas: Rationale for Emerging Therapies.
  Lerario, Antonio Marcondes, Mohan, Dipika R, Hammer, Gary D. Endocr Rev. 2022 Nov 25;43(6):1051-1073. doi:10.1210/endrev/bnac012. Epub .PMID: 35551369
• Bones and adrenal organogenesis: how embryonic osteocalcin influences lifelong adrenal function.
  Dumontet, Typhanie, Hammer, Gary D. J Clin Invest. 2022 Feb 15;132(4):. doi:e157200. Epub .PMID: 35166237
• What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics.
  Juhlin, C Christofer, Bertherat, Jérôme, Giordano, Thomas J, Hammer, Gary D, Sasano, Hironobu, Mete, Ozgur. Endocr Pathol. 2021 Mar32(1):102-133. doi:10.1007/s12022-021-09667-0. Epub 2021 Feb 03.PMID: 33534120
• β-catenin in adrenal zonation and disease.
  Little, Donald W, Dumontet, Typhanie, LaPensee, Christopher R, Hammer, Gary D. Mol Cell Endocrinol. 2021 Feb 15;522:111120. doi:10.1016/j.mce.2020.111120. Epub 2020 Dec 16.PMID: 33338548
• Stem cell function and plasticity in the normal physiology of the adrenal cortex.
  Hammer, Gary D, Basham, Kaitlin J. Mol Cell Endocrinol. 2021 Jan 01;519:111043. doi:10.1016/j.mce.2020.111043. Epub 2020 Oct 12.PMID: 33058950
• Targeted RNAseq of Formalin-Fixed Paraffin-Embedded Tissue to Differentiate Among Benign and Malignant Adrenal Cortical Tumors.
  Plaska, Samuel W, Liu, Chia-Jen, Lim, Jung Soo, Rege, Juilee, Bick, Nolan R, Lerario, Antonio M, Hammer, Gary D, Giordano, Thomas J, Else, Tobias, Tomlins, Scott A, Rainey, William E, Udager, Aaron M. Horm Metab Res. 2020 Aug52(8):607-613. doi:10.1055/a-1212-8803. Epub 2020 Aug 13.PMID: 32791542
• New strategies for applying targeted therapies to adrenocortical carcinoma.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Finco, Isabella, Hammer, Gary D. Curr Opin Endocr Metab Res. 2019 Oct8:72-79. doi:10.1016/j.coemr.2019.07.006. Epub 2019 Aug 06.PMID: 32258822
• Regulation of stem and progenitor cells in the adrenal cortex.
  Finco, Isabella, Mohan, Dipika R, Hammer, Gary D, Lerario, Antonio Marcondes. Curr Opin Endocr Metab Res. 2019 Oct8:66-71. doi:10.1016/j.coemr.2019.07.009. Epub 2019 Aug 06.PMID: 32258821
• Adjuvant Radiation Improves Recurrence-Free Survival and Overall Survival in Adrenocortical Carcinoma.
  Gharzai, Laila A, Green, Michael D, Griffith, Kent A, Else, Tobias, Mayo, Charles S, Hesseltine, Elizabeth, Spratt, Daniel E, Ben-Josef, Edgar, Sabolch, Aaron, Miller, Barbara S, Worden, Francis, Giordano, Thomas J, Hammer, Gary D, Jolly, Shruti. J Clin Endocrinol Metab. 2019 Sep 01;104(9):3743-3750. doi:10.1210/jc.2019-00029. Epub .PMID: 31220287
• Targeted Assessment of Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Else, Tobias, Mukherjee, Bhramar, Almeida, Madson Q, Vinco, Michelle, Rege, Juilee, Mariani, Beatriz M P, Zerbini, Maria Claudia N, Mendonca, Berenice B, Latronico, Ana Claudia, Marie, Suely K N, Rainey, William E, Giordano, Thomas J, Fragoso, Maria Candida B V, Hammer, Gary D. Clin Cancer Res. 2019 Jun 01;25(11):3276-3288. doi:10.1158/1078-0432.CCR-18-2693. Epub 2019 Feb 15.PMID: 30770352
• A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.
  Basham, Kaitlin J, Rodriguez, Stéphanie, Turcu, Adina F, Lerario, Antonio M, Logan, Catriona Y, Rysztak, Madeline R, Gomez-Sanchez, Celso E, Breault, David T, Koo, Bon-Kyoung, Clevers, Hans, Nusse, Roeland, Val, Pierre, Hammer, Gary D. Genes Dev. 2019 Feb 01;33(3-4):209-220. doi:10.1101/gad.317412.118. Epub 2019 Jan 28.PMID: 30692207
• Somatic mutations in adrenocortical carcinoma with primary aldosteronism or hyperreninemic hyperaldosteronism.
  Mouat, Isobel C, Omata, Kei, McDaniel, Andrew S, Hattangady, Namita G, Talapatra, Debnita, Cani, Andi K, Hovelson, Daniel H, Tomlins, Scott A, Rainey, William E, Hammer, Gary D, Giordano, Thomas J, Else, Tobias. Endocr Relat Cancer. 2019 Feb26(2):217-225. doi:10.1530/ERC-18-0385. Epub .PMID: 30475217
• Therapeutic Targets for Adrenocortical Carcinoma in the Genomics Era.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Hammer, Gary D. J Endocr Soc. 2018 Nov 01;2(11):1259-1274. doi:10.1210/js.2018-00197. Epub 2018 Sep 26.PMID: 30402590
• Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands.
  Finco, Isabella, Hammer, Gary D. J Vis Exp. 2018 Oct 02;(140):. doi:58530. Epub 2018 Oct 02.PMID: 30346404
• Longitudinal patterns of recurrence in patients with adrenocortical carcinoma.
  Glenn, Jason A, Else, Tobias, Hughes, David T, Cohen, Mark S, Jolly, Shruti, Giordano, Thomas J, Worden, Francis P, Gauger, Paul G, Hammer, Gary D, Miller, Barbra S. Surgery. 2019 Jan165(1):186-195. doi:10.1016/j.surg.2018.04.068. Epub 2018 Oct 19.PMID: 30343951
• Drug repurposing using high-throughput screening identifies a promising drug combination to treat adrenocortical carcinoma.
  Lerario, Antonio M, Hammer, Gary D. Oncotarget. 2018 Sep 07;9(70):33245-33246. doi:10.18632/oncotarget.26091. Epub 2018 Sep 07.PMID: 30279954
• Oncogenic Signaling Pathways in The Cancer Genome Atlas.
  Sanchez-Vega, Francisco, Mina, Marco, Armenia, Joshua, Chatila, Walid K, Luna, Augustin, La, Konnor C, Dimitriadoy, Sofia, Liu, David L, Kantheti, Havish S, Saghafinia, Sadegh, Chakravarty, Debyani, Daian, Foysal, Gao, Qingsong, Bailey, Matthew H, Liang, Wen-Wei, Foltz, Steven M, Shmulevich, Ilya, Ding, Li, Heins, Zachary, Ochoa, Angelica, Gross, Benjamin, Gao, Jianjiong, Zhang, Hongxin, Kundra, Ritika, Kandoth, Cyriac, Bahceci, Istemi, Dervishi, Leonard, Dogrusoz, Ugur, Zhou, Wanding, Shen, Hui, Laird, Peter W, Way, Gregory P, Greene, Casey S, Liang, Han, Xiao, Yonghong, Wang, Chen, Iavarone, Antonio, Berger, Alice H, Bivona, Trever G, Lazar, Alexander J, Hammer, Gary D, Giordano, Thomas, Kwong, Lawrence N, McArthur, Grant, Huang, Chenfei, Tward, Aaron D, Frederick, Mitchell J, McCormick, Frank, Meyerson, Matthew, , , Van Allen, Eliezer M, Cherniack, Andrew D, Ciriello, Giovanni, Sander, Chris, Schultz, Nikolaus. Cell. 2018 Apr 05;173(2):321-337.e10. doi:10.1016/j.cell.2018.03.035. Epub .PMID: 29625050
• Sonic Hedgehog and WNT Signaling Promote Adrenal Gland Regeneration in Male Mice.
  Finco, Isabella, Lerario, Antonio M, Hammer, Gary D. Endocrinology. 2018 Feb 01;159(2):579-596. doi:10.1210/en.2017-03061. Epub .PMID: 29211850
• Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.
  Xing, Yewei, Morohashi, Ken-Ichirou, Ingraham, Holly A, Hammer, Gary D. Development. 2017 Oct 15;144(20):3798-3807. doi:10.1242/dev.150516. Epub 2017 Sep 11.PMID: 28893949
• Molecular Mechanisms of Stem/Progenitor Cell Maintenance in the Adrenal Cortex.
  Lerario, Antonio Marcondes, Finco, Isabella, LaPensee, Christopher, Hammer, Gary Douglas. Front Endocrinol (Lausanne). 2017 8:52. doi:52. Epub 2017 Mar 23.PMID: 28386245
• Cell signaling pathways in the adrenal cortex: Links to stem/progenitor biology and neoplasia.
  Penny, Morgan K, Finco, Isabella, Hammer, Gary D. Mol Cell Endocrinol. 2017 Apr 15;445:42-54. doi:10.1016/j.mce.2016.12.005. Epub 2016 Dec 08.PMID: 27940298
• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
  Zheng, Siyuan, Cherniack, Andrew D, Dewal, Ninad, Moffitt, Richard A, Danilova, Ludmila, Murray, Bradley A, Lerario, Antonio M, Else, Tobias, Knijnenburg, Theo A, Ciriello, Giovanni, Kim, Seungchan, Assie, Guillaume, Morozova, Olena, Akbani, Rehan, Shih, Juliann, Hoadley, Katherine A, Choueiri, Toni K, Waldmann, Jens, Mete, Ozgur, Robertson, A Gordon, Wu, Hsin-Ta, Raphael, Benjamin J, Shao, Lina, Meyerson, Matthew, Demeure, Michael J, Beuschlein, Felix, Gill, Anthony J, Sidhu, Stan B, Almeida, Madson Q, Fragoso, Maria C B V, Cope, Leslie M, Kebebew, Electron, Habra, Mouhammed A, Whitsett, Timothy G, Bussey, Kimberly J, Rainey, William E, Asa, Sylvia L, Bertherat, Jérôme, Fassnacht, Martin, Wheeler, David A, , , Hammer, Gary D, Giordano, Thomas J, Verhaak, Roel G W. Cancer Cell. 2016 Aug 08;30(2):363. doi:10.1016/j.ccell.2016.07.013. Epub 2016 Aug 08.PMID: 27505681
• Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations.
  Nanba, Kazutaka, Omata, Kei, Tomlins, Scott A, Giordano, Thomas J, Hammer, Gary D, Rainey, William E, Else, Tobias. Eur J Endocrinol. 2016 Aug175(2):K1-6. doi:10.1530/EJE-16-0262. Epub 2016 May 10.PMID: 27165862
• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
  Zheng, Siyuan, Cherniack, Andrew D, Dewal, Ninad, Moffitt, Richard A, Danilova, Ludmila, Murray, Bradley A, Lerario, Antonio M, Else, Tobias, Knijnenburg, Theo A, Ciriello, Giovanni, Kim, Seungchan, Assie, Guillaume, Morozova, Olena, Akbani, Rehan, Shih, Juliann, Hoadley, Katherine A, Choueiri, Toni K, Waldmann, Jens, Mete, Ozgur, Robertson, A Gordon, Wu, Hsin-Ta, Raphael, Benjamin J, Shao, Lina, Meyerson, Matthew, Demeure, Michael J, Beuschlein, Felix, Gill, Anthony J, Sidhu, Stan B, Almeida, Madson Q, Fragoso, Maria C B V, Cope, Leslie M, Kebebew, Electron, Habra, Mouhammed A, Whitsett, Timothy G, Bussey, Kimberly J, Rainey, William E, Asa, Sylvia L, Bertherat, Jérôme, Fassnacht, Martin, Wheeler, David A, , , Hammer, Gary D, Giordano, Thomas J, Verhaak, Roel G W. Cancer Cell. 2016 May 09;29(5):723-736. doi:10.1016/j.ccell.2016.04.002. Epub .PMID: 27165744
• ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs.
  LaPensee, Christopher R, Mann, Jacqueline E, Rainey, William E, Crudo, Valentina, Hunt, Stephen W, Hammer, Gary D. Endocrinology. 2016 May157(5):1775-88. doi:10.1210/en.2015-2052. Epub 2016 Mar 17.PMID: 26986192
• Molecular Heterogeneity in Aldosterone-Producing Adenomas.
  Nanba, Kazutaka, Chen, Andrew X, Omata, Kei, Vinco, Michelle, Giordano, Thomas J, Else, Tobias, Hammer, Gary D, Tomlins, Scott A, Rainey, William E. J Clin Endocrinol Metab. 2016 Mar101(3):999-1007. doi:10.1210/jc.2015-3239. Epub 2016 Jan 14.PMID: 26765578
• Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
  Bornstein, Stefan R, Allolio, Bruno, Arlt, Wiebke, Barthel, Andreas, Don-Wauchope, Andrew, Hammer, Gary D, Husebye, Eystein S, Merke, Deborah P, Murad, M Hassan, Stratakis, Constantine A, Torpy, David J. J Clin Endocrinol Metab. 2016 Feb101(2):364-89. doi:10.1210/jc.2015-1710. Epub 2016 Jan 13.PMID: 26760044
• Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination.
  Lee, Jiwon, Yang, Dong Joo, Lee, Syann, Hammer, Gary D, Kim, Ki Woo, Elmquist, Joel K. Sci Rep. 2016 Jan 11;6:19143. doi:19143. Epub 2016 Jan 11.PMID: 26750456
• 5th International ACC Symposium: Introduction.
  Hammer, Gary D. Horm Cancer. 2016 Feb7(1):1-2. doi:10.1007/s12672-015-0248-8. Epub 2016 Jan 04.PMID: 26728468
• Mouse models of adrenocortical tumors.
  Basham, Kaitlin J, Hung, Holly A, Lerario, Antonio M, Hammer, Gary D. Mol Cell Endocrinol. 2016 Feb 05;421:82-97. doi:10.1016/j.mce.2015.11.031. Epub 2015 Dec 08.PMID: 26678830
• Development of adrenal cortex zonation.
  Xing, Yewei, Lerario, Antonio M, Rainey, William, Hammer, Gary D. Endocrinol Metab Clin North Am. 2015 Jun44(2):243-74. doi:10.1016/j.ecl.2015.02.001. Epub .PMID: 26038200
• Radiographic Characteristics of Adrenal Masses Preceding the Diagnosis of Adrenocortical Cancer.
  Nogueira, T M, Lirov, R, Caoili, E M, Lerario, A M, Miller, B S, Fragoso, M C B V, Dunnick, N R, Hammer, G D, Else, T. Horm Cancer. 2015 Aug6(4):176-81. doi:10.1007/s12672-015-0225-2. Epub 2015 May 29.PMID: 26021762
• Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study.
  Fassnacht, Martin, Berruti, Alfredo, Baudin, Eric, Demeure, Michael J, Gilbert, Jill, Haak, Harm, Kroiss, Matthias, Quinn, David I, Hesseltine, Elizabeth, Ronchi, Cristina L, Terzolo, Massimo, Choueiri, Toni K, Poondru, Srinivasu, Fleege, Tanya, Rorig, Ramona, Chen, Jihong, Stephens, Andrew W, Worden, Francis, Hammer, Gary D. Lancet Oncol. 2015 Apr16(4):426-35. doi:10.1016/S1470-2045(15)70081-1. Epub 2015 Mar 18.PMID: 25795408
• Adjuvant radiation therapy improves local control after surgical resection in patients with localized adrenocortical carcinoma.
  Sabolch, Aaron, Else, Tobias, Griffith, Kent A, Ben-Josef, Edgar, Williams, Andrew, Miller, Barbra S, Worden, Francis, Hammer, Gary D, Jolly, Shruti. Int J Radiat Oncol Biol Phys. 2015 Jun 01;92(2):252-9. doi:10.1016/j.ijrobp.2015.01.007. Epub 2015 Mar 05.PMID: 25754631
• Hedgehog signaling and steroidogenesis.
  Finco, Isabella, LaPensee, Christopher R, Krill, Kenneth T, Hammer, Gary D. Annu Rev Physiol. 2015 77:105-29. doi:10.1146/annurev-physiol-061214-111754. Epub .PMID: 25668018
• Regulation of the adrenocortical stem cell niche: implications for disease.
  Walczak, Elisabeth M, Hammer, Gary D. Nat Rev Endocrinol. 2015 Jan11(1):14-28. doi:10.1038/nrendo.2014.166. Epub 2014 Oct 07.PMID: 25287283
• Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.
  Walczak, Elisabeth M, Kuick, Rork, Finco, Isabella, Bohin, Natacha, Hrycaj, Steven M, Wellik, Deneen M, Hammer, Gary D. Mol Endocrinol. 2014 Sep28(9):1471-86. doi:10.1210/me.2014-1060. Epub 2014 Jul 16.PMID: 25029241
• The combination of insulin-like growth factor receptor 1 (IGF1R) antibody cixutumumab and mitotane as a first-line therapy for patients with recurrent/metastatic adrenocortical carcinoma: a multi-institutional NCI-sponsored trial.
  Lerario, Antonio M, Worden, Francis P, Ramm, Carole A, Hesseltine, Elizabeth A, Stadler, Walter M, Else, Tobias, Shah, Manisha H, Agamah, Edem, Rao, Krishna, Hammer, Gary D. Horm Cancer. 2014 Aug5(4):232-9. doi:10.1007/s12672-014-0182-1. Epub 2014 May 22.PMID: 24849545
• Transcutaneous biopsy of adrenocortical carcinoma is rarely helpful in diagnosis, potentially harmful, but does not affect patient outcome.
  Williams, Andrew R, Hammer, Gary D, Else, Tobias. Eur J Endocrinol. 2014 Jun170(6):829-35. doi:10.1530/EJE-13-1033. Epub .PMID: 24836548
• Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
  Auchus, Richard J, Buschur, Elizabeth O, Chang, Alice Y, Hammer, Gary D, Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W, Jiao, James, Yu, Margaret K. J Clin Endocrinol Metab. 2014 Aug99(8):2763-70. doi:10.1210/jc.2014-1258. Epub 2014 Apr 29.PMID: 24780050
• Adrenocortical carcinoma.
  Else, Tobias, Kim, Alex C, Sabolch, Aaron, Raymond, Victoria M, Kandathil, Asha, Caoili, Elaine M, Jolly, Shruti, Miller, Barbra S, Giordano, Thomas J, Hammer, Gary D. Endocr Rev. 2014 Apr35(2):282-326. doi:10.1210/er.2013-1029. Epub 2013 Dec 20.PMID: 24423978
• Adjuvant therapies and patient and tumor characteristics associated with survival of adult patients with adrenocortical carcinoma.
  Else, Tobias, Williams, Andrew R, Sabolch, Aaron, Jolly, Shruti, Miller, Barbra S, Hammer, Gary D. J Clin Endocrinol Metab. 2014 Feb99(2):455-61. doi:10.1210/jc.2013-2856. Epub 2013 Dec 03.PMID: 24302750
• Prognostic role of overt hypercortisolism in completely operated patients with adrenocortical cancer.
  Berruti, Alfredo, Fassnacht, Martin, Haak, Harm, Else, Tobias, Baudin, Eric, Sperone, Paola, Kroiss, Matthias, Kerkhofs, Thomas, Williams, Andrew R, Ardito, Arianna, Leboulleux, Sophie, Volante, Marco, Deutschbein, Timo, Feelders, Richards, Ronchi, Cristina, Grisanti, Salvatore, Gelderblom, Hans, Porpiglia, Francesco, Papotti, Mauro, Hammer, Gary D, Allolio, Bruno, Terzolo, Massimo. Eur Urol. 2014 Apr65(4):832-8. doi:10.1016/j.eururo.2013.11.006. Epub 2013 Nov 14.PMID: 24268504
• Genetics and epigenetics of adrenocortical tumors.
  Lerario, Antonio M, Moraitis, Andreas, Hammer, Gary D. Mol Cell Endocrinol. 2014 Apr 05;386(1-2):67-84. doi:10.1016/j.mce.2013.10.028. Epub 2013 Nov 09.PMID: 24220673
• Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus.
  Wood, Michelle A, Acharya, Asha, Finco, Isabella, Swonger, Jessica M, Elston, Marlee J, Tallquist, Michelle D, Hammer, Gary D. Development. 2013 Nov140(22):4522-32. doi:10.1242/dev.092775. Epub 2013 Oct 16.PMID: 24131628
• An oncocytic adrenal tumour in a patient with Birt-Hogg-Dubé syndrome.
  Raymond, Victoria M, Long, Jessica M, Everett, Jessica N, Caoili, Elaine M, Gruber, Stephen B, Stoffel, Elena M, Giordano, Thomas J, Hammer, Gary D, Else, Tobias. Clin Endocrinol (Oxf). 2014 Jun80(6):925-7. doi:10.1111/cen.12292. Epub 2013 Aug 05.PMID: 23848572
• Adrenocortical carcinoma is a lynch syndrome-associated cancer.
  Raymond, Victoria M, Everett, Jessica N, Furtado, Larissa V, Gustafson, Shanna L, Jungbluth, Chelsy R, Gruber, Stephen B, Hammer, Gary D, Stoffel, Elena M, Greenson, Joel K, Giordano, Thomas J, Else, Tobias. J Clin Oncol. 2013 Aug 20;31(24):3012-8. doi:10.1200/JCO.2012.48.0988. Epub 2013 Jul 22.PMID: 23752102
• Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex.
  Krill, Kenneth T, Gurdziel, Katherine, Heaton, Joanne H, Simon, Derek P, Hammer, Gary D. Mol Endocrinol. 2013 May27(5):754-68. doi:10.1210/me.2012-1331. Epub 2013 Mar 21.PMID: 23518926
• POD-1 binding to the E-box sequence inhibits SF-1 and StAR expression in human adrenocortical tumor cells.
  França, Monica Malheiros, Ferraz-de-Souza, Bruno, Santos, Mariza Gerdulo, Lerario, Antonio Marcondes, Fragoso, Maria Candida Barisson Villares, Latronico, Ana Claudia, Kuick, Rork D, Hammer, Gary D, Lotfi, Claudimara F P. Mol Cell Endocrinol. 2013 May 22;371(1-2):140-7. doi:10.1016/j.mce.2012.12.029. Epub 2013 Jan 09.PMID: 23313103
• Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
  Raymond, Victoria M, Else, Tobias, Everett, Jessica N, Long, Jessica M, Gruber, Stephen B, Hammer, Gary D. J Clin Endocrinol Metab. 2013 Jan98(1):E119-25. doi:10.1210/jc.2012-2198. Epub 2012 Nov 21.PMID: 23175693
• Resection of adrenocortical carcinoma is less complete and local recurrence occurs sooner and more often after laparoscopic adrenalectomy than after open adrenalectomy.
  Miller, Barbra S, Gauger, Paul G, Hammer, Gary D, Doherty, Gerard M. Surgery. 2012 Dec152(6):1150-7. doi:10.1016/j.surg.2012.08.024. Epub .PMID: 23158185
• Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin.
  Heaton, Joanne H, Wood, Michelle A, Kim, Alex C, Lima, Lorena O, Barlaskar, Ferdous M, Almeida, Madson Q, Fragoso, Maria C B V, Kuick, Rork, Lerario, Antonio M, Simon, Derek P, Soares, Ibere C, Starnes, Elisabeth, Thomas, Dafydd G, Latronico, Ana C, Giordano, Thomas J, Hammer, Gary D. Am J Pathol. 2012 Sep181(3):1017-33. doi:10.1016/j.ajpath.2012.05.026. Epub 2012 Jul 15.PMID: 22800756
• Worsening central sarcopenia and increasing intra-abdominal fat correlate with decreased survival in patients with adrenocortical carcinoma.
  Miller, Barbra S, Ignatoski, Kathleen M, Daignault, Stephanie, Lindland, Ceit, Doherty, Megan, Gauger, Paul G, Hammer, Gary D, Wang, Stewart C, Doherty, Gerard M, , . World J Surg. 2012 Jul36(7):1509-16. doi:10.1007/s00268-012-1581-5. Epub .PMID: 22526034
• Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma.
  Simon, Derek P, Giordano, Thomas J, Hammer, Gary D. Clin Cancer Res. 2012 May 01;18(9):2452-64. doi:10.1158/1078-0432.CCR-11-2371. Epub 2012 Mar 16.PMID: 22427350
• Adrenocortical stem and progenitor cells: implications for adrenocortical carcinoma.
  Simon, Derek P, Hammer, Gary D. Mol Cell Endocrinol. 2012 Mar 31;351(1):2-11. doi:10.1016/j.mce.2011.12.006. Epub 2012 Jan 13.PMID: 22266195
• Adrenal cancer: clinical advances.
  Hammer, Gary D, Fassnacht, Martin, Lalli, Enzo. Horm Cancer. 2011 Dec2(6):323. doi:10.1007/s12672-011-0092-4. Epub .PMID: 22173667
• Aged PROP1 deficient dwarf mice maintain ACTH production.
  Nasonkin, Igor O, Ward, Robert D, Bavers, David L, Beuschlein, Felix, Mortensen, Amanda H, Keegan, Catherine E, Hammer, Gary D, Camper, Sally A. PLoS One. 2011 6(12):e28355. doi:e28355. Epub 2011 Dec 01.PMID: 22145038
• Adrenal cancer: scientific advances.
  Hammer, Gary D, Fassnacht, Martin, Lalli, Enzo. Mol Cell Endocrinol. 2012 Mar 31;351(1):1. doi:10.1016/j.mce.2011.11.010. Epub 2011 Nov 15.PMID: 22108436
• Evidence of adrenal failure in aging Dax1-deficient mice.
  Scheys, Joshua O, Heaton, Joanne H, Hammer, Gary D. Endocrinology. 2011 Sep152(9):3430-9. doi:10.1210/en.2010-0986. Epub 2011 Jul 05.PMID: 21733829
• Mebendazole monotherapy and long-term disease control in metastatic adrenocortical carcinoma.
  Dobrosotskaya, Irina Y, Hammer, Gary D, Schteingart, David E, Maturen, Katherine E, Worden, Francis P. Endocr Pract. 2011 17(3):e59-62. doi:10.4158/EP10390.CR. Epub .PMID: 21454232
• Adrenocortical stem and progenitor cells: unifying model of two proposed origins.
  Wood, Michelle A, Hammer, Gary D. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):206-12. doi:10.1016/j.mce.2010.11.012. Epub 2010 Nov 20.PMID: 21094677
• Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.
  Kelly, Victoria R, Xu, Bin, Kuick, Rork, Koenig, Ronald J, Hammer, Gary D. Mol Endocrinol. 2010 Dec24(12):2281-91. doi:10.1210/me.2010-0133. Epub 2010 Oct 13.PMID: 20943815
• LRH-1 and Nanog regulate Dax1 transcription in mouse embryonic stem cells.
  Kelly, Victoria R, Hammer, Gary D. Mol Cell Endocrinol. 2011 Jan 30;332(1-2):116-24. doi:10.1016/j.mce.2010.10.003. Epub 2010 Oct 16.PMID: 20937355
• Proposal for modification of the ENSAT staging system for adrenocortical carcinoma using tumor grade.
  Miller, Barbra S, Gauger, Paul G, Hammer, Gary D, Giordano, Thomas J, Doherty, Gerard M. Langenbecks Arch Surg. 2010 Sep395(7):955-61. doi:10.1007/s00423-010-0698-y. Epub 2010 Aug 09.PMID: 20694732
• Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.
  Garcia-Perez, Jose L, Morell, Maria, Scheys, Joshua O, Kulpa, Deanna A, Morell, Santiago, Carter, Christoph C, Hammer, Gary D, Collins, Kathleen L, O'Shea, K Sue, Menendez, Pablo, Moran, John V. Nature. 2010 Aug 05;466(7307):769-73. doi:10.1038/nature09209. Epub .PMID: 20686575
• GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer.
  Watson, Richard L, Spalding, Aaron C, Zielske, Steven P, Morgan, Meredith, Kim, Alex C, Bommer, Guido T, Eldar-Finkelman, Hagit, Giordano, Thomas, Fearon, Eric R, Hammer, Gary D, Lawrence, Theodore S, Ben-Josef, Edgar. Neoplasia. 2010 May12(5):357-65. doi:. Epub .PMID: 20454507
• Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma.
  Miller, B S, Ammori, J B, Gauger, P G, Broome, J T, Hammer, G D, Doherty, G M. World J Surg. 2010 Jun34(6):1380-5. doi:10.1007/s00268-010-0532-2. Epub .PMID: 20372905
• Inhibin-A antagonizes TGFbeta2 signaling by down-regulating cell surface expression of the TGFbeta coreceptor betaglycan.
  Looyenga, Brendan D, Wiater, Ezra, Vale, Wylie, Hammer, Gary D. Mol Endocrinol. 2010 Mar24(3):608-20. doi:10.1210/me.2008-0374. Epub 2010 Feb 16.PMID: 20160125
• Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma.
  Haluska, Paul, Worden, Frank, Olmos, David, Yin, Donghua, Schteingart, David, Batzel, Gretchen N, Paccagnella, M Luisa, de Bono, Johann S, Gualberto, Antonio, Hammer, Gary D. Cancer Chemother Pharmacol. 2010 Mar65(4):765-73. doi:10.1007/s00280-009-1083-9. Epub 2009 Aug 02.PMID: 19649631
• Management of adrenocortical carcinoma.
  Strosberg, Jonathan R, Hammer, Gary D, Doherty, Gerard M. J Natl Compr Canc Netw. 2009 Jul7(7):752-8; quiz 759. doi:. Epub .PMID: 19635227
• Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.
  Else, Tobias, Trovato, Alessia, Kim, Alex C, Wu, Yipin, Ferguson, David O, Kuick, Rork D, Lucas, Peter C, Hammer, Gary D. Cancer Cell. 2009 Jun 02;15(6):465-76. doi:10.1016/j.ccr.2009.04.011. Epub .PMID: 19477426
• In search of adrenocortical stem and progenitor cells.
  Kim, Alex C, Barlaskar, Ferdous M, Heaton, Joanne H, Else, Tobias, Kelly, Victoria R, Krill, Kenneth T, Scheys, Joshua O, Simon, Derek P, Trovato, Alessia, Yang, Wei-Hsiung, Hammer, Gary D. Endocr Rev. 2009 May30(3):241-63. doi:10.1210/er.2008-0039. Epub 2009 Apr 29.PMID: 19403887
• Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.
  Kim, A, Giordano, T-J, Kuick, R, Serecky, K, Hammer, G D. Ann Endocrinol (Paris). 2009 Jun70(3):156. doi:10.1016/j.ando.2009.02.006. Epub 2009 Mar 14.PMID: 19286162
• Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.
  Xu, Bin, Yang, Wei-Hsiung, Gerin, Isabelle, Hu, Chang-Deng, Hammer, Gary D, Koenig, Ronald J. Mol Cell Biol. 2009 Apr29(7):1719-34. doi:10.1128/MCB.01010-08. Epub 2009 Feb 02.PMID: 19188450
• The role of radiologic studies in the evaluation and management of primary hyperaldosteronism.
  White, Matthew L, Gauger, Paul G, Doherty, Gerard M, Cho, Kyung J, Thompson, Norman W, Hammer, Gary D, Miller, Barbra S. Surgery. 2008 Dec144(6):926-33; discussion 933. doi:10.1016/j.surg.2008.07.025. Epub .PMID: 19040999
• SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation.
  Yang, Wei-Hsiung, Heaton, Joanne H, Brevig, Holly, Mukherjee, Sarmistha, Iñiguez-Lluhí, Jorge A, Hammer, Gary D. Mol Cell Biol. 2009 Feb29(3):613-25. doi:10.1128/MCB.00295-08. Epub 2008 Nov 17.PMID: 19015234
• Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.
  Barlaskar, Ferdous M, Spalding, Aaron C, Heaton, Joanne H, Kuick, Rork, Kim, Alex C, Thomas, Dafydd G, Giordano, Thomas J, Ben-Josef, Edgar, Hammer, Gary D. J Clin Endocrinol Metab. 2009 Jan94(1):204-12. doi:10.1210/jc.2008-1456. Epub 2008 Oct 14.PMID: 18854392
• Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex.
  Kim, Alex C, Reuter, Anne L, Zubair, Mohamad, Else, Tobias, Serecky, Kerri, Bingham, Nathan C, Lavery, Gareth G, Parker, Keith L, Hammer, Gary D. Development. 2008 Aug135(15):2593-602. doi:10.1242/dev.021493. Epub 2008 Jul 03.PMID: 18599507
• Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells.
  Rui, Xianliang, Tsao, Jennivine, Scheys, Joshua O, Hammer, Gary D, Schimmer, Bernard P. Endocrinology. 2008 Jul149(7):3668-78. doi:10.1210/en.2008-0203. Epub 2008 Apr 03.PMID: 18388192
• Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
  Else, Tobias, Giordano, Thomas J, Hammer, Gary D. J Clin Endocrinol Metab. 2008 Apr93(4):1442-9. doi:10.1210/jc.2007-1840. Epub 2008 Jan 15.PMID: 18198226
• Tpp1/Acd maintains genomic stability through a complex role in telomere protection.
  Else, Tobias, Theisen, Brian K, Wu, Yipin, Hutz, Janna E, Keegan, Catherine E, Hammer, Gary D, Ferguson, David O. Chromosome Res. 2007 15(8):1001-13. doi:10.1007/s10577-007-1175-5. Epub 2008 Jan 09.PMID: 18185984
• The molecular genetics of adrenocortical carcinoma.
  Barlaskar, Ferdous M, Hammer, Gary D. Rev Endocr Metab Disord. 2007 Dec8(4):343-8. doi:. Epub .PMID: 17934868
• Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.
  Looyenga, Brendan D, Hammer, Gary D. Mol Endocrinol. 2007 Oct21(10):2440-57. doi:. Epub 2007 Jul 24.PMID: 17652186
• Telomere protection by mammalian Pot1 requires interaction with Tpp1.
  Hockemeyer, Dirk, Palm, Wilhelm, Else, Tobias, Daniels, Jan-Peter, Takai, Kaori K, Ye, Jeffrey Z-S, Keegan, Catherine E, de Lange, Titia, Hammer, Gary D. Nat Struct Mol Biol. 2007 Aug14(8):754-61. doi:. Epub 2007 Jul 15.PMID: 17632522
• Novel polymorphisms and lack of mutations in the ACD gene in patients with ACTH resistance syndromes.
  Keegan, Catherine E, Hutz, Janna E, Krause, Andrea S, Koehler, Katrin, Metherell, Louise A, Boikos, Sosipatros, Stergiopoulos, Sotirios, Clark, Adrian J L, Stratakis, Constantine A, Huebner, Angela, Hammer, Gary D. Clin Endocrinol (Oxf). 2007 Aug67(2):168-74. doi:. Epub 2007 Apr 27.PMID: 17466001
• Adrenocortical cells with stem/progenitor cell properties: recent advances.
  Kim, Alex C, Hammer, Gary D. Mol Cell Endocrinol. 2007 Feb265-266:10-6. doi:. Epub 2007 Jan 19.PMID: 17240045
• Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis.
  Lichtenauer, Urs D, Duchniewicz, Marlena, Kolanczyk, Mateusz, Hoeflich, Andreas, Hahner, Stephanie, Else, Tobias, Bicknell, Andrew B, Zemojtel, Tomasz, Stallings, Nancy R, Schulte, Dominik M, Kamps, Mark P, Hammer, Gary D, Scheele, Jürgen S, Beuschlein, Felix. Endocrinology. 2007 Feb148(2):693-704. doi:. Epub 2006 Nov 02.PMID: 17082260
• Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the adrenal cortex.
  Looyenga, Brendan D, Hammer, Gary D. Mol Endocrinol. 2006 Nov20(11):2848-63. doi:. Epub 2006 Jul 27.PMID: 16873442
• Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex.
  Gummow, Brian M, Scheys, Joshua O, Cancelli, Victoria R, Hammer, Gary D. Mol Endocrinol. 2006 Nov20(11):2711-23. doi:. Epub 2006 Jul 20.PMID: 16857744
• Gonadectomy in mice of the inbred strain CE/J induces proliferation of sub-capsular adrenal cells expressing gonadal marker genes.
  Johnsen, Inga K, Slawik, Marc, Shapiro, Igor, Hartmann, Michaela F, Wudy, Stefan A, Looyenga, Brendan D, Hammer, Gary D, Reincke, Martin, Beuschlein, Felix. J Endocrinol. 2006 Jul190(1):47-57. doi:. Epub .PMID: 16837610
• IMAGe association and congenital adrenal hypoplasia: no disease-causing mutations found in the ACD gene.
  Hutz, Janna E, Krause, Andrea S, Achermann, John C, Vilain, Eric, Tauber, Maïthé, Lecointre, Claudine, McCabe, Edward R B, Hammer, Gary D, Keegan, Catherine E. Mol Genet Metab. 2006 May88(1):66-70. doi:. Epub 2006 Feb 28.PMID: 16504561
• Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function.
  Winnay, Jonathon N, Xu, Jianming, O'Malley, Bert W, Hammer, Gary D. Endocrinology. 2006 Mar147(3):1322-32. doi:. Epub 2005 Dec 08.PMID: 16339206
• Genetic analysis of adrenal absence: agenesis and aplasia.
  Else, Tobias, Hammer, Gary D. Trends Endocrinol Metab. 2005 Dec16(10):458-68. doi:. Epub 2005 Nov 04.PMID: 16275119
• Management of patients with adrenal cancer: recommendations of an international consensus conference.
  Schteingart, D E, Doherty, G M, Gauger, P G, Giordano, T J, Hammer, G D, Korobkin, M, Worden, F P. Endocr Relat Cancer. 2005 Sep12(3):667-80. doi:. Epub .PMID: 16172199
• Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.
  Winnay, Jonathon N, Hammer, Gary D. Mol Endocrinol. 2006 Jan20(1):147-66. doi:. Epub 2005 Aug 18.PMID: 16109736
• Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
  Park, Susan Y, Meeks, Joshua J, Raverot, Gerald, Pfaff, Liza E, Weiss, Jeffrey, Hammer, Gary D, Jameson, J Larry. Development. 2005 May132(10):2415-23. doi:. Epub 2005 Apr 13.PMID: 15829514
• Mechanistic roles of inhibin as a tumor suppressor in the adrenal cortex.
  Looyenga, Brendan, Beuschlein, Felix, Nilson, John, Hammer, Gary D. Endocr Res. 2004 Nov30(4):585-6. doi:. Epub .PMID: 15666795
• Minireview: transcriptional regulation of adrenocortical development.
  Hammer, Gary D, Parker, Keith L, Schimmer, Bernard P. Endocrinology. 2005 Mar146(3):1018-24. doi:. Epub 2004 Dec 16.PMID: 15604207
• Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results.
  Hammer, Gary D, Tyrrell, J Blake, Lamborn, Kathleen R, Applebury, Carol B, Hannegan, Elizabeth T, Bell, Scott, Rahl, Riva, Lu, Amy, Wilson, Charles B. J Clin Endocrinol Metab. 2004 Dec89(12):6348-57. doi:. Epub .PMID: 15579802
• Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
  Keegan, Catherine E, Hutz, Janna E, Else, Tobias, Adamska, Maja, Shah, Sonalee P, Kent, Amy E, Howes, John M, Beamer, Wesley G, Hammer, Gary D. Hum Mol Genet. 2005 Jan 01;14(1):113-23. doi:. Epub 2004 Nov 10.PMID: 15537664
• Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis.
  Beuschlein, F, Looyenga, B D, Reincke, M, Hammer, G D. Horm Metab Res. 2004 Jun36(6):392-6. doi:. Epub .PMID: 15241730
• T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
  Kennell, Jennifer A, O'Leary, Erin E, Gummow, Brian M, Hammer, Gary D, MacDougald, Ormond A. Mol Cell Biol. 2003 Aug23(15):5366-75. doi:. Epub .PMID: 12861022
• Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.
  Beuschlein, Felix, Looyenga, Brendan D, Bleasdale, Stephanie E, Mutch, Chris, Bavers, David L, Parlow, Albert F, Nilson, John H, Hammer, Gary D. Mol Cell Biol. 2003 Jun23(11):3951-64. doi:. Epub .PMID: 12748296
• Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene.
  Gummow, Brian M, Winnay, Jonathon N, Hammer, Gary D. J Biol Chem. 2003 Jul 18;278(29):26572-9. doi:. Epub 2003 May 05.PMID: 12732619
• SF-1, DAX-1, and acd: molecular determinants of adrenocortical growth and steroidogenesis.
  Beuschlein, F, Keegan, C E, Bavers, D L, Mutch, C, Hutz, J E, Shah, S, Ulrich-Lai, Y M, Engeland, W C, Jeffs, B, Jameson, J L, Hammer, G D. Endocr Res. 2002 Nov28(4):597-607. doi:. Epub .PMID: 12530669
• Recent insights into organogenesis of the adrenal cortex.
  Keegan, Catherine E, Hammer, Gary D. Trends Endocrinol Metab. 2002 Jul13(5):200-8. doi:. Epub .PMID: 12185666
• Steroidogenic factor-1 is essential for compensatory adrenal growth following unilateral adrenalectomy.
  Beuschlein, Felix, Mutch, Chris, Bavers, David L, Ulrich-Lai, Yvonne M, Engeland, William C, Keegan, Catherine, Hammer, Gary D. Endocrinology. 2002 Aug143(8):3122-35. doi:. Epub .PMID: 12130578
• Ectopic pro-opiomelanocortin syndrome.
  Beuschlein, Felix, Hammer, Gary D. Endocrinol Metab Clin North Am. 2002 Mar31(1):191-234. doi:. Epub .PMID: 12055989
• Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1.
  Babu, Poda Suresh, Bavers, David L, Beuschlein, Felix, Shah, Sonalee, Jeffs, Baxter, Jameson, J Larry, Hammer, Gary D. Endocrinology. 2002 Feb143(2):665-73. doi:. Epub .PMID: 11796523
• Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis.
  Babu, P S, Bavers, D L, Shah, S, Hammer, G D. Endocr Res. 2000 Nov26(4):985-94. doi:. Epub .PMID: 11196480
• Steroidogenic factor-1: its role in endocrine organ development and differentiation.
  Hammer, G D, Ingraham, H A. Front Neuroendocrinol. 1999 Jul20(3):199-223. doi:. Epub .PMID: 10433862
• Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress.
  Hammer, G D, Krylova, I, Zhang, Y, Darimont, B D, Simpson, K, Weigel, N L, Ingraham, H A. Mol Cell. 1999 Apr3(4):521-6. doi:. Epub .PMID: 10230405
• Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.
  Nachtigal, M W, Hirokawa, Y, Enyeart-VanHouten, D L, Flanagan, J N, Hammer, G D, Ingraham, H A. Cell. 1998 May 01;93(3):445-54. doi:. Epub .PMID: 9590178
• Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
  Low, M J, Liu, B, Hammer, G D, Rubinstein, M, Allen, R G. J Biol Chem. 1993 Nov 25;268(33):24967-75. doi:. Epub .PMID: 8227058
• Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
  Liu, B, Hammer, G D, Rubinstein, M, Mortrud, M, Low, M J. Mol Cell Biol. 1992 Sep12(9):3978-90. doi:. Epub .PMID: 1508198
• Pituitary corticotroph hyperplasia in rats implanted with a medullary thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deoxyribonucleic acid expression vector.
  Asa, S L, Kovacs, K, Hammer, G D, Liu, B, Roos, B A, Low, M J. Endocrinology. 1992 Aug131(2):715-20. doi:. Epub .PMID: 1322279
• Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-adrenal axis in transkaryotic rats.
  Hammer, G D, Mueller, G, Liu, B, Petrides, J S, Roos, B A, Low, M J. Endocrinology. 1992 Apr130(4):1975-85. doi:. Epub .PMID: 1312432
• Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.
  Hammer, G D, Fairchild-Huntress, V, Low, M J. Mol Endocrinol. 1990 Nov4(11):1689-97. doi:. Epub .PMID: 2177840
• The effects of naloxone administered into the periaqueductal gray on shock-elicited freezing behavior in the rat.
  Hammer, G D, Kapp, B S. Behav Neural Biol. 1986 Sep46(2):189-95. doi:. Epub .PMID: 3767831

• Targeting of a New Node in Lipid Metabolism as a Potential Treatment Strategy for ACC.
  LaPensee, Christopher R, Hammer, Gary D. Endocrinology. 2023 Jan 09;164(3):. doi:bqad003. Epub .PMID: 36636840
• American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary.
  Yip, Linwah, Duh, Quan-Yang, Wachtel, Heather, Jimenez, Camilo, Sturgeon, Cord, Lee, Cortney, Velázquez-Fernández, David, Berber, Eren, Hammer, Gary D, Bancos, Irina, Lee, James A, Marko, Jamie, Morris-Wiseman, Lilah F, Hughes, Marybeth S, Livhits, Masha J, Han, Mi-Ah, Smith, Philip W, Wilhelm, Scott, Asa, Sylvia L, Fahey, Thomas J, McKenzie, Travis J, Strong, Vivian E, Perrier, Nancy D. JAMA Surg. 2022 Oct 01;157(10):870-877. doi:10.1001/jamasurg.2022.3544. Epub .PMID: 35976622
• Update on Biology and Genomics of Adrenocortical Carcinomas: Rationale for Emerging Therapies.
  Lerario, Antonio Marcondes, Mohan, Dipika R, Hammer, Gary D. Endocr Rev. 2022 Nov 25;43(6):1051-1073. doi:10.1210/endrev/bnac012. Epub .PMID: 35551369
• Bones and adrenal organogenesis: how embryonic osteocalcin influences lifelong adrenal function.
  Dumontet, Typhanie, Hammer, Gary D. J Clin Invest. 2022 Feb 15;132(4):. doi:e157200. Epub .PMID: 35166237
• What Did We Learn from the Molecular Biology of Adrenal Cortical Neoplasia? From Histopathology to Translational Genomics.
  Juhlin, C Christofer, Bertherat, Jérôme, Giordano, Thomas J, Hammer, Gary D, Sasano, Hironobu, Mete, Ozgur. Endocr Pathol. 2021 Mar32(1):102-133. doi:10.1007/s12022-021-09667-0. Epub 2021 Feb 03.PMID: 33534120
• β-catenin in adrenal zonation and disease.
  Little, Donald W, Dumontet, Typhanie, LaPensee, Christopher R, Hammer, Gary D. Mol Cell Endocrinol. 2021 Feb 15;522:111120. doi:10.1016/j.mce.2020.111120. Epub 2020 Dec 16.PMID: 33338548
• Stem cell function and plasticity in the normal physiology of the adrenal cortex.
  Hammer, Gary D, Basham, Kaitlin J. Mol Cell Endocrinol. 2021 Jan 01;519:111043. doi:10.1016/j.mce.2020.111043. Epub 2020 Oct 12.PMID: 33058950
• Targeted RNAseq of Formalin-Fixed Paraffin-Embedded Tissue to Differentiate Among Benign and Malignant Adrenal Cortical Tumors.
  Plaska, Samuel W, Liu, Chia-Jen, Lim, Jung Soo, Rege, Juilee, Bick, Nolan R, Lerario, Antonio M, Hammer, Gary D, Giordano, Thomas J, Else, Tobias, Tomlins, Scott A, Rainey, William E, Udager, Aaron M. Horm Metab Res. 2020 Aug52(8):607-613. doi:10.1055/a-1212-8803. Epub 2020 Aug 13.PMID: 32791542
• New strategies for applying targeted therapies to adrenocortical carcinoma.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Finco, Isabella, Hammer, Gary D. Curr Opin Endocr Metab Res. 2019 Oct8:72-79. doi:10.1016/j.coemr.2019.07.006. Epub 2019 Aug 06.PMID: 32258822
• Regulation of stem and progenitor cells in the adrenal cortex.
  Finco, Isabella, Mohan, Dipika R, Hammer, Gary D, Lerario, Antonio Marcondes. Curr Opin Endocr Metab Res. 2019 Oct8:66-71. doi:10.1016/j.coemr.2019.07.009. Epub 2019 Aug 06.PMID: 32258821
• Adjuvant Radiation Improves Recurrence-Free Survival and Overall Survival in Adrenocortical Carcinoma.
  Gharzai, Laila A, Green, Michael D, Griffith, Kent A, Else, Tobias, Mayo, Charles S, Hesseltine, Elizabeth, Spratt, Daniel E, Ben-Josef, Edgar, Sabolch, Aaron, Miller, Barbara S, Worden, Francis, Giordano, Thomas J, Hammer, Gary D, Jolly, Shruti. J Clin Endocrinol Metab. 2019 Sep 01;104(9):3743-3750. doi:10.1210/jc.2019-00029. Epub .PMID: 31220287
• Targeted Assessment of Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Else, Tobias, Mukherjee, Bhramar, Almeida, Madson Q, Vinco, Michelle, Rege, Juilee, Mariani, Beatriz M P, Zerbini, Maria Claudia N, Mendonca, Berenice B, Latronico, Ana Claudia, Marie, Suely K N, Rainey, William E, Giordano, Thomas J, Fragoso, Maria Candida B V, Hammer, Gary D. Clin Cancer Res. 2019 Jun 01;25(11):3276-3288. doi:10.1158/1078-0432.CCR-18-2693. Epub 2019 Feb 15.PMID: 30770352
• A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.
  Basham, Kaitlin J, Rodriguez, Stéphanie, Turcu, Adina F, Lerario, Antonio M, Logan, Catriona Y, Rysztak, Madeline R, Gomez-Sanchez, Celso E, Breault, David T, Koo, Bon-Kyoung, Clevers, Hans, Nusse, Roeland, Val, Pierre, Hammer, Gary D. Genes Dev. 2019 Feb 01;33(3-4):209-220. doi:10.1101/gad.317412.118. Epub 2019 Jan 28.PMID: 30692207
• Somatic mutations in adrenocortical carcinoma with primary aldosteronism or hyperreninemic hyperaldosteronism.
  Mouat, Isobel C, Omata, Kei, McDaniel, Andrew S, Hattangady, Namita G, Talapatra, Debnita, Cani, Andi K, Hovelson, Daniel H, Tomlins, Scott A, Rainey, William E, Hammer, Gary D, Giordano, Thomas J, Else, Tobias. Endocr Relat Cancer. 2019 Feb26(2):217-225. doi:10.1530/ERC-18-0385. Epub .PMID: 30475217
• Therapeutic Targets for Adrenocortical Carcinoma in the Genomics Era.
  Mohan, Dipika R, Lerario, Antonio Marcondes, Hammer, Gary D. J Endocr Soc. 2018 Nov 01;2(11):1259-1274. doi:10.1210/js.2018-00197. Epub 2018 Sep 26.PMID: 30402590
• Isolation, Fixation, and Immunofluorescence Imaging of Mouse Adrenal Glands.
  Finco, Isabella, Hammer, Gary D. J Vis Exp. 2018 Oct 02;(140):. doi:58530. Epub 2018 Oct 02.PMID: 30346404
• Longitudinal patterns of recurrence in patients with adrenocortical carcinoma.
  Glenn, Jason A, Else, Tobias, Hughes, David T, Cohen, Mark S, Jolly, Shruti, Giordano, Thomas J, Worden, Francis P, Gauger, Paul G, Hammer, Gary D, Miller, Barbra S. Surgery. 2019 Jan165(1):186-195. doi:10.1016/j.surg.2018.04.068. Epub 2018 Oct 19.PMID: 30343951
• Drug repurposing using high-throughput screening identifies a promising drug combination to treat adrenocortical carcinoma.
  Lerario, Antonio M, Hammer, Gary D. Oncotarget. 2018 Sep 07;9(70):33245-33246. doi:10.18632/oncotarget.26091. Epub 2018 Sep 07.PMID: 30279954
• Oncogenic Signaling Pathways in The Cancer Genome Atlas.
  Sanchez-Vega, Francisco, Mina, Marco, Armenia, Joshua, Chatila, Walid K, Luna, Augustin, La, Konnor C, Dimitriadoy, Sofia, Liu, David L, Kantheti, Havish S, Saghafinia, Sadegh, Chakravarty, Debyani, Daian, Foysal, Gao, Qingsong, Bailey, Matthew H, Liang, Wen-Wei, Foltz, Steven M, Shmulevich, Ilya, Ding, Li, Heins, Zachary, Ochoa, Angelica, Gross, Benjamin, Gao, Jianjiong, Zhang, Hongxin, Kundra, Ritika, Kandoth, Cyriac, Bahceci, Istemi, Dervishi, Leonard, Dogrusoz, Ugur, Zhou, Wanding, Shen, Hui, Laird, Peter W, Way, Gregory P, Greene, Casey S, Liang, Han, Xiao, Yonghong, Wang, Chen, Iavarone, Antonio, Berger, Alice H, Bivona, Trever G, Lazar, Alexander J, Hammer, Gary D, Giordano, Thomas, Kwong, Lawrence N, McArthur, Grant, Huang, Chenfei, Tward, Aaron D, Frederick, Mitchell J, McCormick, Frank, Meyerson, Matthew, , , Van Allen, Eliezer M, Cherniack, Andrew D, Ciriello, Giovanni, Sander, Chris, Schultz, Nikolaus. Cell. 2018 Apr 05;173(2):321-337.e10. doi:10.1016/j.cell.2018.03.035. Epub .PMID: 29625050
• Sonic Hedgehog and WNT Signaling Promote Adrenal Gland Regeneration in Male Mice.
  Finco, Isabella, Lerario, Antonio M, Hammer, Gary D. Endocrinology. 2018 Feb 01;159(2):579-596. doi:10.1210/en.2017-03061. Epub .PMID: 29211850
• Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.
  Xing, Yewei, Morohashi, Ken-Ichirou, Ingraham, Holly A, Hammer, Gary D. Development. 2017 Oct 15;144(20):3798-3807. doi:10.1242/dev.150516. Epub 2017 Sep 11.PMID: 28893949
• Molecular Mechanisms of Stem/Progenitor Cell Maintenance in the Adrenal Cortex.
  Lerario, Antonio Marcondes, Finco, Isabella, LaPensee, Christopher, Hammer, Gary Douglas. Front Endocrinol (Lausanne). 2017 8:52. doi:52. Epub 2017 Mar 23.PMID: 28386245
• Cell signaling pathways in the adrenal cortex: Links to stem/progenitor biology and neoplasia.
  Penny, Morgan K, Finco, Isabella, Hammer, Gary D. Mol Cell Endocrinol. 2017 Apr 15;445:42-54. doi:10.1016/j.mce.2016.12.005. Epub 2016 Dec 08.PMID: 27940298
• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
  Zheng, Siyuan, Cherniack, Andrew D, Dewal, Ninad, Moffitt, Richard A, Danilova, Ludmila, Murray, Bradley A, Lerario, Antonio M, Else, Tobias, Knijnenburg, Theo A, Ciriello, Giovanni, Kim, Seungchan, Assie, Guillaume, Morozova, Olena, Akbani, Rehan, Shih, Juliann, Hoadley, Katherine A, Choueiri, Toni K, Waldmann, Jens, Mete, Ozgur, Robertson, A Gordon, Wu, Hsin-Ta, Raphael, Benjamin J, Shao, Lina, Meyerson, Matthew, Demeure, Michael J, Beuschlein, Felix, Gill, Anthony J, Sidhu, Stan B, Almeida, Madson Q, Fragoso, Maria C B V, Cope, Leslie M, Kebebew, Electron, Habra, Mouhammed A, Whitsett, Timothy G, Bussey, Kimberly J, Rainey, William E, Asa, Sylvia L, Bertherat, Jérôme, Fassnacht, Martin, Wheeler, David A, , , Hammer, Gary D, Giordano, Thomas J, Verhaak, Roel G W. Cancer Cell. 2016 Aug 08;30(2):363. doi:10.1016/j.ccell.2016.07.013. Epub 2016 Aug 08.PMID: 27505681
• Double adrenocortical adenomas harboring independent KCNJ5 and PRKACA somatic mutations.
  Nanba, Kazutaka, Omata, Kei, Tomlins, Scott A, Giordano, Thomas J, Hammer, Gary D, Rainey, William E, Else, Tobias. Eur J Endocrinol. 2016 Aug175(2):K1-6. doi:10.1530/EJE-16-0262. Epub 2016 May 10.PMID: 27165862
• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma.
  Zheng, Siyuan, Cherniack, Andrew D, Dewal, Ninad, Moffitt, Richard A, Danilova, Ludmila, Murray, Bradley A, Lerario, Antonio M, Else, Tobias, Knijnenburg, Theo A, Ciriello, Giovanni, Kim, Seungchan, Assie, Guillaume, Morozova, Olena, Akbani, Rehan, Shih, Juliann, Hoadley, Katherine A, Choueiri, Toni K, Waldmann, Jens, Mete, Ozgur, Robertson, A Gordon, Wu, Hsin-Ta, Raphael, Benjamin J, Shao, Lina, Meyerson, Matthew, Demeure, Michael J, Beuschlein, Felix, Gill, Anthony J, Sidhu, Stan B, Almeida, Madson Q, Fragoso, Maria C B V, Cope, Leslie M, Kebebew, Electron, Habra, Mouhammed A, Whitsett, Timothy G, Bussey, Kimberly J, Rainey, William E, Asa, Sylvia L, Bertherat, Jérôme, Fassnacht, Martin, Wheeler, David A, , , Hammer, Gary D, Giordano, Thomas J, Verhaak, Roel G W. Cancer Cell. 2016 May 09;29(5):723-736. doi:10.1016/j.ccell.2016.04.002. Epub .PMID: 27165744
• ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs.
  LaPensee, Christopher R, Mann, Jacqueline E, Rainey, William E, Crudo, Valentina, Hunt, Stephen W, Hammer, Gary D. Endocrinology. 2016 May157(5):1775-88. doi:10.1210/en.2015-2052. Epub 2016 Mar 17.PMID: 26986192
• Molecular Heterogeneity in Aldosterone-Producing Adenomas.
  Nanba, Kazutaka, Chen, Andrew X, Omata, Kei, Vinco, Michelle, Giordano, Thomas J, Else, Tobias, Hammer, Gary D, Tomlins, Scott A, Rainey, William E. J Clin Endocrinol Metab. 2016 Mar101(3):999-1007. doi:10.1210/jc.2015-3239. Epub 2016 Jan 14.PMID: 26765578
• Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline.
  Bornstein, Stefan R, Allolio, Bruno, Arlt, Wiebke, Barthel, Andreas, Don-Wauchope, Andrew, Hammer, Gary D, Husebye, Eystein S, Merke, Deborah P, Murad, M Hassan, Stratakis, Constantine A, Torpy, David J. J Clin Endocrinol Metab. 2016 Feb101(2):364-89. doi:10.1210/jc.2015-1710. Epub 2016 Jan 13.PMID: 26760044
• Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination.
  Lee, Jiwon, Yang, Dong Joo, Lee, Syann, Hammer, Gary D, Kim, Ki Woo, Elmquist, Joel K. Sci Rep. 2016 Jan 11;6:19143. doi:19143. Epub 2016 Jan 11.PMID: 26750456
• 5th International ACC Symposium: Introduction.
  Hammer, Gary D. Horm Cancer. 2016 Feb7(1):1-2. doi:10.1007/s12672-015-0248-8. Epub 2016 Jan 04.PMID: 26728468
• Mouse models of adrenocortical tumors.
  Basham, Kaitlin J, Hung, Holly A, Lerario, Antonio M, Hammer, Gary D. Mol Cell Endocrinol. 2016 Feb 05;421:82-97. doi:10.1016/j.mce.2015.11.031. Epub 2015 Dec 08.PMID: 26678830
• Development of adrenal cortex zonation.
  Xing, Yewei, Lerario, Antonio M, Rainey, William, Hammer, Gary D. Endocrinol Metab Clin North Am. 2015 Jun44(2):243-74. doi:10.1016/j.ecl.2015.02.001. Epub .PMID: 26038200
• Radiographic Characteristics of Adrenal Masses Preceding the Diagnosis of Adrenocortical Cancer.
  Nogueira, T M, Lirov, R, Caoili, E M, Lerario, A M, Miller, B S, Fragoso, M C B V, Dunnick, N R, Hammer, G D, Else, T. Horm Cancer. 2015 Aug6(4):176-81. doi:10.1007/s12672-015-0225-2. Epub 2015 May 29.PMID: 26021762
• Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study.
  Fassnacht, Martin, Berruti, Alfredo, Baudin, Eric, Demeure, Michael J, Gilbert, Jill, Haak, Harm, Kroiss, Matthias, Quinn, David I, Hesseltine, Elizabeth, Ronchi, Cristina L, Terzolo, Massimo, Choueiri, Toni K, Poondru, Srinivasu, Fleege, Tanya, Rorig, Ramona, Chen, Jihong, Stephens, Andrew W, Worden, Francis, Hammer, Gary D. Lancet Oncol. 2015 Apr16(4):426-35. doi:10.1016/S1470-2045(15)70081-1. Epub 2015 Mar 18.PMID: 25795408
• Adjuvant radiation therapy improves local control after surgical resection in patients with localized adrenocortical carcinoma.
  Sabolch, Aaron, Else, Tobias, Griffith, Kent A, Ben-Josef, Edgar, Williams, Andrew, Miller, Barbra S, Worden, Francis, Hammer, Gary D, Jolly, Shruti. Int J Radiat Oncol Biol Phys. 2015 Jun 01;92(2):252-9. doi:10.1016/j.ijrobp.2015.01.007. Epub 2015 Mar 05.PMID: 25754631
• Hedgehog signaling and steroidogenesis.
  Finco, Isabella, LaPensee, Christopher R, Krill, Kenneth T, Hammer, Gary D. Annu Rev Physiol. 2015 77:105-29. doi:10.1146/annurev-physiol-061214-111754. Epub .PMID: 25668018
• Regulation of the adrenocortical stem cell niche: implications for disease.
  Walczak, Elisabeth M, Hammer, Gary D. Nat Rev Endocrinol. 2015 Jan11(1):14-28. doi:10.1038/nrendo.2014.166. Epub 2014 Oct 07.PMID: 25287283
• Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.
  Walczak, Elisabeth M, Kuick, Rork, Finco, Isabella, Bohin, Natacha, Hrycaj, Steven M, Wellik, Deneen M, Hammer, Gary D. Mol Endocrinol. 2014 Sep28(9):1471-86. doi:10.1210/me.2014-1060. Epub 2014 Jul 16.PMID: 25029241
• The combination of insulin-like growth factor receptor 1 (IGF1R) antibody cixutumumab and mitotane as a first-line therapy for patients with recurrent/metastatic adrenocortical carcinoma: a multi-institutional NCI-sponsored trial.
  Lerario, Antonio M, Worden, Francis P, Ramm, Carole A, Hesseltine, Elizabeth A, Stadler, Walter M, Else, Tobias, Shah, Manisha H, Agamah, Edem, Rao, Krishna, Hammer, Gary D. Horm Cancer. 2014 Aug5(4):232-9. doi:10.1007/s12672-014-0182-1. Epub 2014 May 22.PMID: 24849545
• Transcutaneous biopsy of adrenocortical carcinoma is rarely helpful in diagnosis, potentially harmful, but does not affect patient outcome.
  Williams, Andrew R, Hammer, Gary D, Else, Tobias. Eur J Endocrinol. 2014 Jun170(6):829-35. doi:10.1530/EJE-13-1033. Epub .PMID: 24836548
• Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
  Auchus, Richard J, Buschur, Elizabeth O, Chang, Alice Y, Hammer, Gary D, Ramm, Carole, Madrigal, David, Wang, George, Gonzalez, Martha, Xu, Xu Steven, Smit, Johan W, Jiao, James, Yu, Margaret K. J Clin Endocrinol Metab. 2014 Aug99(8):2763-70. doi:10.1210/jc.2014-1258. Epub 2014 Apr 29.PMID: 24780050
• Adrenocortical carcinoma.
  Else, Tobias, Kim, Alex C, Sabolch, Aaron, Raymond, Victoria M, Kandathil, Asha, Caoili, Elaine M, Jolly, Shruti, Miller, Barbra S, Giordano, Thomas J, Hammer, Gary D. Endocr Rev. 2014 Apr35(2):282-326. doi:10.1210/er.2013-1029. Epub 2013 Dec 20.PMID: 24423978
• Adjuvant therapies and patient and tumor characteristics associated with survival of adult patients with adrenocortical carcinoma.
  Else, Tobias, Williams, Andrew R, Sabolch, Aaron, Jolly, Shruti, Miller, Barbra S, Hammer, Gary D. J Clin Endocrinol Metab. 2014 Feb99(2):455-61. doi:10.1210/jc.2013-2856. Epub 2013 Dec 03.PMID: 24302750
• Prognostic role of overt hypercortisolism in completely operated patients with adrenocortical cancer.
  Berruti, Alfredo, Fassnacht, Martin, Haak, Harm, Else, Tobias, Baudin, Eric, Sperone, Paola, Kroiss, Matthias, Kerkhofs, Thomas, Williams, Andrew R, Ardito, Arianna, Leboulleux, Sophie, Volante, Marco, Deutschbein, Timo, Feelders, Richards, Ronchi, Cristina, Grisanti, Salvatore, Gelderblom, Hans, Porpiglia, Francesco, Papotti, Mauro, Hammer, Gary D, Allolio, Bruno, Terzolo, Massimo. Eur Urol. 2014 Apr65(4):832-8. doi:10.1016/j.eururo.2013.11.006. Epub 2013 Nov 14.PMID: 24268504
• Genetics and epigenetics of adrenocortical tumors.
  Lerario, Antonio M, Moraitis, Andreas, Hammer, Gary D. Mol Cell Endocrinol. 2014 Apr 05;386(1-2):67-84. doi:10.1016/j.mce.2013.10.028. Epub 2013 Nov 09.PMID: 24220673
• Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus.
  Wood, Michelle A, Acharya, Asha, Finco, Isabella, Swonger, Jessica M, Elston, Marlee J, Tallquist, Michelle D, Hammer, Gary D. Development. 2013 Nov140(22):4522-32. doi:10.1242/dev.092775. Epub 2013 Oct 16.PMID: 24131628
• An oncocytic adrenal tumour in a patient with Birt-Hogg-Dubé syndrome.
  Raymond, Victoria M, Long, Jessica M, Everett, Jessica N, Caoili, Elaine M, Gruber, Stephen B, Stoffel, Elena M, Giordano, Thomas J, Hammer, Gary D, Else, Tobias. Clin Endocrinol (Oxf). 2014 Jun80(6):925-7. doi:10.1111/cen.12292. Epub 2013 Aug 05.PMID: 23848572
• Adrenocortical carcinoma is a lynch syndrome-associated cancer.
  Raymond, Victoria M, Everett, Jessica N, Furtado, Larissa V, Gustafson, Shanna L, Jungbluth, Chelsy R, Gruber, Stephen B, Hammer, Gary D, Stoffel, Elena M, Greenson, Joel K, Giordano, Thomas J, Else, Tobias. J Clin Oncol. 2013 Aug 20;31(24):3012-8. doi:10.1200/JCO.2012.48.0988. Epub 2013 Jul 22.PMID: 23752102
• Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex.
  Krill, Kenneth T, Gurdziel, Katherine, Heaton, Joanne H, Simon, Derek P, Hammer, Gary D. Mol Endocrinol. 2013 May27(5):754-68. doi:10.1210/me.2012-1331. Epub 2013 Mar 21.PMID: 23518926
• POD-1 binding to the E-box sequence inhibits SF-1 and StAR expression in human adrenocortical tumor cells.
  França, Monica Malheiros, Ferraz-de-Souza, Bruno, Santos, Mariza Gerdulo, Lerario, Antonio Marcondes, Fragoso, Maria Candida Barisson Villares, Latronico, Ana Claudia, Kuick, Rork D, Hammer, Gary D, Lotfi, Claudimara F P. Mol Cell Endocrinol. 2013 May 22;371(1-2):140-7. doi:10.1016/j.mce.2012.12.029. Epub 2013 Jan 09.PMID: 23313103
• Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
  Raymond, Victoria M, Else, Tobias, Everett, Jessica N, Long, Jessica M, Gruber, Stephen B, Hammer, Gary D. J Clin Endocrinol Metab. 2013 Jan98(1):E119-25. doi:10.1210/jc.2012-2198. Epub 2012 Nov 21.PMID: 23175693
• Resection of adrenocortical carcinoma is less complete and local recurrence occurs sooner and more often after laparoscopic adrenalectomy than after open adrenalectomy.
  Miller, Barbra S, Gauger, Paul G, Hammer, Gary D, Doherty, Gerard M. Surgery. 2012 Dec152(6):1150-7. doi:10.1016/j.surg.2012.08.024. Epub .PMID: 23158185
• Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin.
  Heaton, Joanne H, Wood, Michelle A, Kim, Alex C, Lima, Lorena O, Barlaskar, Ferdous M, Almeida, Madson Q, Fragoso, Maria C B V, Kuick, Rork, Lerario, Antonio M, Simon, Derek P, Soares, Ibere C, Starnes, Elisabeth, Thomas, Dafydd G, Latronico, Ana C, Giordano, Thomas J, Hammer, Gary D. Am J Pathol. 2012 Sep181(3):1017-33. doi:10.1016/j.ajpath.2012.05.026. Epub 2012 Jul 15.PMID: 22800756
• Worsening central sarcopenia and increasing intra-abdominal fat correlate with decreased survival in patients with adrenocortical carcinoma.
  Miller, Barbra S, Ignatoski, Kathleen M, Daignault, Stephanie, Lindland, Ceit, Doherty, Megan, Gauger, Paul G, Hammer, Gary D, Wang, Stewart C, Doherty, Gerard M, , . World J Surg. 2012 Jul36(7):1509-16. doi:10.1007/s00268-012-1581-5. Epub .PMID: 22526034
• Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma.
  Simon, Derek P, Giordano, Thomas J, Hammer, Gary D. Clin Cancer Res. 2012 May 01;18(9):2452-64. doi:10.1158/1078-0432.CCR-11-2371. Epub 2012 Mar 16.PMID: 22427350
• Adrenocortical stem and progenitor cells: implications for adrenocortical carcinoma.
  Simon, Derek P, Hammer, Gary D. Mol Cell Endocrinol. 2012 Mar 31;351(1):2-11. doi:10.1016/j.mce.2011.12.006. Epub 2012 Jan 13.PMID: 22266195
• Adrenal cancer: clinical advances.
  Hammer, Gary D, Fassnacht, Martin, Lalli, Enzo. Horm Cancer. 2011 Dec2(6):323. doi:10.1007/s12672-011-0092-4. Epub .PMID: 22173667
• Aged PROP1 deficient dwarf mice maintain ACTH production.
  Nasonkin, Igor O, Ward, Robert D, Bavers, David L, Beuschlein, Felix, Mortensen, Amanda H, Keegan, Catherine E, Hammer, Gary D, Camper, Sally A. PLoS One. 2011 6(12):e28355. doi:e28355. Epub 2011 Dec 01.PMID: 22145038
• Adrenal cancer: scientific advances.
  Hammer, Gary D, Fassnacht, Martin, Lalli, Enzo. Mol Cell Endocrinol. 2012 Mar 31;351(1):1. doi:10.1016/j.mce.2011.11.010. Epub 2011 Nov 15.PMID: 22108436
• Evidence of adrenal failure in aging Dax1-deficient mice.
  Scheys, Joshua O, Heaton, Joanne H, Hammer, Gary D. Endocrinology. 2011 Sep152(9):3430-9. doi:10.1210/en.2010-0986. Epub 2011 Jul 05.PMID: 21733829
• Mebendazole monotherapy and long-term disease control in metastatic adrenocortical carcinoma.
  Dobrosotskaya, Irina Y, Hammer, Gary D, Schteingart, David E, Maturen, Katherine E, Worden, Francis P. Endocr Pract. 2011 17(3):e59-62. doi:10.4158/EP10390.CR. Epub .PMID: 21454232
• Adrenocortical stem and progenitor cells: unifying model of two proposed origins.
  Wood, Michelle A, Hammer, Gary D. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):206-12. doi:10.1016/j.mce.2010.11.012. Epub 2010 Nov 20.PMID: 21094677
• Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.
  Kelly, Victoria R, Xu, Bin, Kuick, Rork, Koenig, Ronald J, Hammer, Gary D. Mol Endocrinol. 2010 Dec24(12):2281-91. doi:10.1210/me.2010-0133. Epub 2010 Oct 13.PMID: 20943815
• LRH-1 and Nanog regulate Dax1 transcription in mouse embryonic stem cells.
  Kelly, Victoria R, Hammer, Gary D. Mol Cell Endocrinol. 2011 Jan 30;332(1-2):116-24. doi:10.1016/j.mce.2010.10.003. Epub 2010 Oct 16.PMID: 20937355
• Proposal for modification of the ENSAT staging system for adrenocortical carcinoma using tumor grade.
  Miller, Barbra S, Gauger, Paul G, Hammer, Gary D, Giordano, Thomas J, Doherty, Gerard M. Langenbecks Arch Surg. 2010 Sep395(7):955-61. doi:10.1007/s00423-010-0698-y. Epub 2010 Aug 09.PMID: 20694732
• Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells.
  Garcia-Perez, Jose L, Morell, Maria, Scheys, Joshua O, Kulpa, Deanna A, Morell, Santiago, Carter, Christoph C, Hammer, Gary D, Collins, Kathleen L, O'Shea, K Sue, Menendez, Pablo, Moran, John V. Nature. 2010 Aug 05;466(7307):769-73. doi:10.1038/nature09209. Epub .PMID: 20686575
• GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer.
  Watson, Richard L, Spalding, Aaron C, Zielske, Steven P, Morgan, Meredith, Kim, Alex C, Bommer, Guido T, Eldar-Finkelman, Hagit, Giordano, Thomas, Fearon, Eric R, Hammer, Gary D, Lawrence, Theodore S, Ben-Josef, Edgar. Neoplasia. 2010 May12(5):357-65. doi:. Epub .PMID: 20454507
• Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinoma.
  Miller, B S, Ammori, J B, Gauger, P G, Broome, J T, Hammer, G D, Doherty, G M. World J Surg. 2010 Jun34(6):1380-5. doi:10.1007/s00268-010-0532-2. Epub .PMID: 20372905
• Inhibin-A antagonizes TGFbeta2 signaling by down-regulating cell surface expression of the TGFbeta coreceptor betaglycan.
  Looyenga, Brendan D, Wiater, Ezra, Vale, Wylie, Hammer, Gary D. Mol Endocrinol. 2010 Mar24(3):608-20. doi:10.1210/me.2008-0374. Epub 2010 Feb 16.PMID: 20160125
• Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma.
  Haluska, Paul, Worden, Frank, Olmos, David, Yin, Donghua, Schteingart, David, Batzel, Gretchen N, Paccagnella, M Luisa, de Bono, Johann S, Gualberto, Antonio, Hammer, Gary D. Cancer Chemother Pharmacol. 2010 Mar65(4):765-73. doi:10.1007/s00280-009-1083-9. Epub 2009 Aug 02.PMID: 19649631
• Management of adrenocortical carcinoma.
  Strosberg, Jonathan R, Hammer, Gary D, Doherty, Gerard M. J Natl Compr Canc Netw. 2009 Jul7(7):752-8; quiz 759. doi:. Epub .PMID: 19635227
• Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.
  Else, Tobias, Trovato, Alessia, Kim, Alex C, Wu, Yipin, Ferguson, David O, Kuick, Rork D, Lucas, Peter C, Hammer, Gary D. Cancer Cell. 2009 Jun 02;15(6):465-76. doi:10.1016/j.ccr.2009.04.011. Epub .PMID: 19477426
• In search of adrenocortical stem and progenitor cells.
  Kim, Alex C, Barlaskar, Ferdous M, Heaton, Joanne H, Else, Tobias, Kelly, Victoria R, Krill, Kenneth T, Scheys, Joshua O, Simon, Derek P, Trovato, Alessia, Yang, Wei-Hsiung, Hammer, Gary D. Endocr Rev. 2009 May30(3):241-63. doi:10.1210/er.2008-0039. Epub 2009 Apr 29.PMID: 19403887
• Wnt/betacatenin signaling in adrenocortical stem/progenitor cells: implications for adrenocortical carcinoma.
  Kim, A, Giordano, T-J, Kuick, R, Serecky, K, Hammer, G D. Ann Endocrinol (Paris). 2009 Jun70(3):156. doi:10.1016/j.ando.2009.02.006. Epub 2009 Mar 14.PMID: 19286162
• Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis.
  Xu, Bin, Yang, Wei-Hsiung, Gerin, Isabelle, Hu, Chang-Deng, Hammer, Gary D, Koenig, Ronald J. Mol Cell Biol. 2009 Apr29(7):1719-34. doi:10.1128/MCB.01010-08. Epub 2009 Feb 02.PMID: 19188450
• The role of radiologic studies in the evaluation and management of primary hyperaldosteronism.
  White, Matthew L, Gauger, Paul G, Doherty, Gerard M, Cho, Kyung J, Thompson, Norman W, Hammer, Gary D, Miller, Barbra S. Surgery. 2008 Dec144(6):926-33; discussion 933. doi:10.1016/j.surg.2008.07.025. Epub .PMID: 19040999
• SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation.
  Yang, Wei-Hsiung, Heaton, Joanne H, Brevig, Holly, Mukherjee, Sarmistha, Iñiguez-Lluhí, Jorge A, Hammer, Gary D. Mol Cell Biol. 2009 Feb29(3):613-25. doi:10.1128/MCB.00295-08. Epub 2008 Nov 17.PMID: 19015234
• Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.
  Barlaskar, Ferdous M, Spalding, Aaron C, Heaton, Joanne H, Kuick, Rork, Kim, Alex C, Thomas, Dafydd G, Giordano, Thomas J, Ben-Josef, Edgar, Hammer, Gary D. J Clin Endocrinol Metab. 2009 Jan94(1):204-12. doi:10.1210/jc.2008-1456. Epub 2008 Oct 14.PMID: 18854392
• Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex.
  Kim, Alex C, Reuter, Anne L, Zubair, Mohamad, Else, Tobias, Serecky, Kerri, Bingham, Nathan C, Lavery, Gareth G, Parker, Keith L, Hammer, Gary D. Development. 2008 Aug135(15):2593-602. doi:10.1242/dev.021493. Epub 2008 Jul 03.PMID: 18599507
• Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells.
  Rui, Xianliang, Tsao, Jennivine, Scheys, Joshua O, Hammer, Gary D, Schimmer, Bernard P. Endocrinology. 2008 Jul149(7):3668-78. doi:10.1210/en.2008-0203. Epub 2008 Apr 03.PMID: 18388192
• Evaluation of telomere length maintenance mechanisms in adrenocortical carcinoma.
  Else, Tobias, Giordano, Thomas J, Hammer, Gary D. J Clin Endocrinol Metab. 2008 Apr93(4):1442-9. doi:10.1210/jc.2007-1840. Epub 2008 Jan 15.PMID: 18198226
• Tpp1/Acd maintains genomic stability through a complex role in telomere protection.
  Else, Tobias, Theisen, Brian K, Wu, Yipin, Hutz, Janna E, Keegan, Catherine E, Hammer, Gary D, Ferguson, David O. Chromosome Res. 2007 15(8):1001-13. doi:10.1007/s10577-007-1175-5. Epub 2008 Jan 09.PMID: 18185984
• The molecular genetics of adrenocortical carcinoma.
  Barlaskar, Ferdous M, Hammer, Gary D. Rev Endocr Metab Disord. 2007 Dec8(4):343-8. doi:. Epub .PMID: 17934868
• Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery.
  Looyenga, Brendan D, Hammer, Gary D. Mol Endocrinol. 2007 Oct21(10):2440-57. doi:. Epub 2007 Jul 24.PMID: 17652186
• Telomere protection by mammalian Pot1 requires interaction with Tpp1.
  Hockemeyer, Dirk, Palm, Wilhelm, Else, Tobias, Daniels, Jan-Peter, Takai, Kaori K, Ye, Jeffrey Z-S, Keegan, Catherine E, de Lange, Titia, Hammer, Gary D. Nat Struct Mol Biol. 2007 Aug14(8):754-61. doi:. Epub 2007 Jul 15.PMID: 17632522
• Novel polymorphisms and lack of mutations in the ACD gene in patients with ACTH resistance syndromes.
  Keegan, Catherine E, Hutz, Janna E, Krause, Andrea S, Koehler, Katrin, Metherell, Louise A, Boikos, Sosipatros, Stergiopoulos, Sotirios, Clark, Adrian J L, Stratakis, Constantine A, Huebner, Angela, Hammer, Gary D. Clin Endocrinol (Oxf). 2007 Aug67(2):168-74. doi:. Epub 2007 Apr 27.PMID: 17466001
• Adrenocortical cells with stem/progenitor cell properties: recent advances.
  Kim, Alex C, Hammer, Gary D. Mol Cell Endocrinol. 2007 Feb265-266:10-6. doi:. Epub 2007 Jan 19.PMID: 17240045
• Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis.
  Lichtenauer, Urs D, Duchniewicz, Marlena, Kolanczyk, Mateusz, Hoeflich, Andreas, Hahner, Stephanie, Else, Tobias, Bicknell, Andrew B, Zemojtel, Tomasz, Stallings, Nancy R, Schulte, Dominik M, Kamps, Mark P, Hammer, Gary D, Scheele, Jürgen S, Beuschlein, Felix. Endocrinology. 2007 Feb148(2):693-704. doi:. Epub 2006 Nov 02.PMID: 17082260
• Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the adrenal cortex.
  Looyenga, Brendan D, Hammer, Gary D. Mol Endocrinol. 2006 Nov20(11):2848-63. doi:. Epub 2006 Jul 27.PMID: 16873442
• Reciprocal regulation of a glucocorticoid receptor-steroidogenic factor-1 transcription complex on the Dax-1 promoter by glucocorticoids and adrenocorticotropic hormone in the adrenal cortex.
  Gummow, Brian M, Scheys, Joshua O, Cancelli, Victoria R, Hammer, Gary D. Mol Endocrinol. 2006 Nov20(11):2711-23. doi:. Epub 2006 Jul 20.PMID: 16857744
• Gonadectomy in mice of the inbred strain CE/J induces proliferation of sub-capsular adrenal cells expressing gonadal marker genes.
  Johnsen, Inga K, Slawik, Marc, Shapiro, Igor, Hartmann, Michaela F, Wudy, Stefan A, Looyenga, Brendan D, Hammer, Gary D, Reincke, Martin, Beuschlein, Felix. J Endocrinol. 2006 Jul190(1):47-57. doi:. Epub .PMID: 16837610
• IMAGe association and congenital adrenal hypoplasia: no disease-causing mutations found in the ACD gene.
  Hutz, Janna E, Krause, Andrea S, Achermann, John C, Vilain, Eric, Tauber, Maïthé, Lecointre, Claudine, McCabe, Edward R B, Hammer, Gary D, Keegan, Catherine E. Mol Genet Metab. 2006 May88(1):66-70. doi:. Epub 2006 Feb 28.PMID: 16504561
• Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function.
  Winnay, Jonathon N, Xu, Jianming, O'Malley, Bert W, Hammer, Gary D. Endocrinology. 2006 Mar147(3):1322-32. doi:. Epub 2005 Dec 08.PMID: 16339206
• Genetic analysis of adrenal absence: agenesis and aplasia.
  Else, Tobias, Hammer, Gary D. Trends Endocrinol Metab. 2005 Dec16(10):458-68. doi:. Epub 2005 Nov 04.PMID: 16275119
• Management of patients with adrenal cancer: recommendations of an international consensus conference.
  Schteingart, D E, Doherty, G M, Gauger, P G, Giordano, T J, Hammer, G D, Korobkin, M, Worden, F P. Endocr Relat Cancer. 2005 Sep12(3):667-80. doi:. Epub .PMID: 16172199
• Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.
  Winnay, Jonathon N, Hammer, Gary D. Mol Endocrinol. 2006 Jan20(1):147-66. doi:. Epub 2005 Aug 18.PMID: 16109736
• Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development.
  Park, Susan Y, Meeks, Joshua J, Raverot, Gerald, Pfaff, Liza E, Weiss, Jeffrey, Hammer, Gary D, Jameson, J Larry. Development. 2005 May132(10):2415-23. doi:. Epub 2005 Apr 13.PMID: 15829514
• Mechanistic roles of inhibin as a tumor suppressor in the adrenal cortex.
  Looyenga, Brendan, Beuschlein, Felix, Nilson, John, Hammer, Gary D. Endocr Res. 2004 Nov30(4):585-6. doi:. Epub .PMID: 15666795
• Minireview: transcriptional regulation of adrenocortical development.
  Hammer, Gary D, Parker, Keith L, Schimmer, Bernard P. Endocrinology. 2005 Mar146(3):1018-24. doi:. Epub 2004 Dec 16.PMID: 15604207
• Transsphenoidal microsurgery for Cushing's disease: initial outcome and long-term results.
  Hammer, Gary D, Tyrrell, J Blake, Lamborn, Kathleen R, Applebury, Carol B, Hannegan, Elizabeth T, Bell, Scott, Rahl, Riva, Lu, Amy, Wilson, Charles B. J Clin Endocrinol Metab. 2004 Dec89(12):6348-57. doi:. Epub .PMID: 15579802
• Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator.
  Keegan, Catherine E, Hutz, Janna E, Else, Tobias, Adamska, Maja, Shah, Sonalee P, Kent, Amy E, Howes, John M, Beamer, Wesley G, Hammer, Gary D. Hum Mol Genet. 2005 Jan 01;14(1):113-23. doi:. Epub 2004 Nov 10.PMID: 15537664
• Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis.
  Beuschlein, F, Looyenga, B D, Reincke, M, Hammer, G D. Horm Metab Res. 2004 Jun36(6):392-6. doi:. Epub .PMID: 15241730
• T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors.
  Kennell, Jennifer A, O'Leary, Erin E, Gummow, Brian M, Hammer, Gary D, MacDougald, Ormond A. Mol Cell Biol. 2003 Aug23(15):5366-75. doi:. Epub .PMID: 12861022
• Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice.
  Beuschlein, Felix, Looyenga, Brendan D, Bleasdale, Stephanie E, Mutch, Chris, Bavers, David L, Parlow, Albert F, Nilson, John H, Hammer, Gary D. Mol Cell Biol. 2003 Jun23(11):3951-64. doi:. Epub .PMID: 12748296
• Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin alpha gene.
  Gummow, Brian M, Winnay, Jonathon N, Hammer, Gary D. J Biol Chem. 2003 Jul 18;278(29):26572-9. doi:. Epub 2003 May 05.PMID: 12732619
• SF-1, DAX-1, and acd: molecular determinants of adrenocortical growth and steroidogenesis.
  Beuschlein, F, Keegan, C E, Bavers, D L, Mutch, C, Hutz, J E, Shah, S, Ulrich-Lai, Y M, Engeland, W C, Jeffs, B, Jameson, J L, Hammer, G D. Endocr Res. 2002 Nov28(4):597-607. doi:. Epub .PMID: 12530669
• Recent insights into organogenesis of the adrenal cortex.
  Keegan, Catherine E, Hammer, Gary D. Trends Endocrinol Metab. 2002 Jul13(5):200-8. doi:. Epub .PMID: 12185666
• Steroidogenic factor-1 is essential for compensatory adrenal growth following unilateral adrenalectomy.
  Beuschlein, Felix, Mutch, Chris, Bavers, David L, Ulrich-Lai, Yvonne M, Engeland, William C, Keegan, Catherine, Hammer, Gary D. Endocrinology. 2002 Aug143(8):3122-35. doi:. Epub .PMID: 12130578
• Ectopic pro-opiomelanocortin syndrome.
  Beuschlein, Felix, Hammer, Gary D. Endocrinol Metab Clin North Am. 2002 Mar31(1):191-234. doi:. Epub .PMID: 12055989
• Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1.
  Babu, Poda Suresh, Bavers, David L, Beuschlein, Felix, Shah, Sonalee, Jeffs, Baxter, Jameson, J Larry, Hammer, Gary D. Endocrinology. 2002 Feb143(2):665-73. doi:. Epub .PMID: 11796523
• Role of phosphorylation, gene dosage and Dax-1 in SF-1 mediated steroidogenesis.
  Babu, P S, Bavers, D L, Shah, S, Hammer, G D. Endocr Res. 2000 Nov26(4):985-94. doi:. Epub .PMID: 11196480
• Steroidogenic factor-1: its role in endocrine organ development and differentiation.
  Hammer, G D, Ingraham, H A. Front Neuroendocrinol. 1999 Jul20(3):199-223. doi:. Epub .PMID: 10433862
• Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress.
  Hammer, G D, Krylova, I, Zhang, Y, Darimont, B D, Simpson, K, Weigel, N L, Ingraham, H A. Mol Cell. 1999 Apr3(4):521-6. doi:. Epub .PMID: 10230405
• Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.
  Nachtigal, M W, Hirokawa, Y, Enyeart-VanHouten, D L, Flanagan, J N, Hammer, G D, Ingraham, H A. Cell. 1998 May 01;93(3):445-54. doi:. Epub .PMID: 9590178
• Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene.
  Low, M J, Liu, B, Hammer, G D, Rubinstein, M, Allen, R G. J Biol Chem. 1993 Nov 25;268(33):24967-75. doi:. Epub .PMID: 8227058
• Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.
  Liu, B, Hammer, G D, Rubinstein, M, Mortrud, M, Low, M J. Mol Cell Biol. 1992 Sep12(9):3978-90. doi:. Epub .PMID: 1508198
• Pituitary corticotroph hyperplasia in rats implanted with a medullary thyroid carcinoma cell line transfected with a corticotropin-releasing hormone complementary deoxyribonucleic acid expression vector.
  Asa, S L, Kovacs, K, Hammer, G D, Liu, B, Roos, B A, Low, M J. Endocrinology. 1992 Aug131(2):715-20. doi:. Epub .PMID: 1322279
• Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-adrenal axis in transkaryotic rats.
  Hammer, G D, Mueller, G, Liu, B, Petrides, J S, Roos, B A, Low, M J. Endocrinology. 1992 Apr130(4):1975-85. doi:. Epub .PMID: 1312432
• Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice.
  Hammer, G D, Fairchild-Huntress, V, Low, M J. Mol Endocrinol. 1990 Nov4(11):1689-97. doi:. Epub .PMID: 2177840
• The effects of naloxone administered into the periaqueductal gray on shock-elicited freezing behavior in the rat.
  Hammer, G D, Kapp, B S. Behav Neural Biol. 1986 Sep46(2):189-95. doi:. Epub .PMID: 3767831